RAF Typhoon FGR4s have operated alongside French warplanes in a joint strike targeting an underground arms cache in Syria used by the IS group, per a report from the British defence ministry.
The facility, identified by reconnaissance, was thought to be containing munitions and bombs, the release indicated, and was located in hills just above the historic site of Palmyra in the heart of Syria.
"The RAF jets utilized laser-guided Paveway IV weapons to strike a several access tunnels providing entry to the depot... early reports suggest the strike was effective," the ministry announced.
There was no evidence of any civilian casualties in the attack conducted Saturday night and each participating jet made a safe return, the MoD added.
The Typhoon fighters were assisted by a Voyager aerial refuelling aircraft.
IS - also known as Daesh - established extremist governance over large swathes of Syria and Iraq prior to its 2019 collapse.
"This action underscores our UK leadership, and resolve to stand shoulder to shoulder with allied nations, to eradicate any resurgence of Daesh and their dangerous and violent ideologies in the region," UK Defence Secretary the Defence Secretary said.
RAF aircraft have performed overwatch operations over Syria to "forestall any attempted resurgence" of the group following its routing at the battle of Baghuz in 2019, the authorities noted.
"I must thank the personnel of our armed forces who took part in this operation for their professionalism and their courage," Healey added. "They were among numerous British troops on duty over Christmas and New Year. This mission, to remove terrorist threats who endanger our way of life, shows how British military are prepared to act, all year round, ensuring Britain's security domestically and powerful internationally."
In December, the American forces conducted what it described as a "large-scale strike" targeting Daesh sites in Syria, subsequent to an ambush resulted in the deaths of two US servicemembers and a civilian interpreter in Palmyra.
The United Nations says Islamic State still maintains between 5,000 and 7,000 militants in Syria and Iraq.
